Skin boosters and injectables – which is best for you?

The world of aesthetic treatments is constantly evolving, offering incredible non-surgical options to rejuvenate and restore skin health. Gone are the days when injectables were only about adding volume; today, the focus is on bio-remodelling and cellular regeneration.

If you’ve been looking to combat dullness, laxity, and fine lines, you’ve likely heard the buzz around treatments like Profhilo, Jalupro, and the exciting new class of Polynucleotides. But with so many options, how do you choose the one that’s right for your skin goals?

The difference lies not just in their catchy names, but in their core ingredients and the fundamental way they work with your body’s natural processes.

  • Hyaluronic Acid (HA) Boosters (like Profhilo and Jalupro) are hydration powerhouses, using HA combined with essential nutrients (like Amino Acids) to plump, smooth, and boost collagen production.
  • Polynucleotides are the cutting-edge regenerative option, working at a DNA level to signal cells to repair, regenerate, and strengthen tissue from the inside out.

Choosing the right treatment depends on whether your priority is immediate hydration, structural support, or deep cellular repair.

To help you decode the science and select your perfect skin cocktail, we’ve broken down the key differences between the leading treatments in one easy-to-read comparison table:


CategoryPolynucleotidesJalupro HMWJalupro Super HydroProfhilo
Main IngredientPurified DNA fragments (from salmon/trout)Hyaluronic Acid + Amino AcidsHyaluronic Acid + 7 Amino Acids & 3 PeptidesHigh concentration of pure Hyaluronic Acid
ActionDeep regeneration, activates fibroblasts, improves cell repairHydrates & stimulates collagen via fibroblast activationMulti-level hydration, structural support & ligament regenerationBio-remodelling, hydrates & minimally stimulates collagen & elastin
ResultsGradual – full effect after the final session (6–8 weeks)Faster-acting (initial effects within 5–7 days)Quicker visible hydration and deeper collagen regenerationModerate – hydration/plumping visible within 4 weeks
Best ForScarring, mild laxity, under-eye hollowing, rosacea-prone skinFine lines, mild to moderate laxity, general skin quality boostMild to deep volume loss, sagging, advanced skin ageing (firming & restructuring)Skin laxity, dullness, fine lines (best for global hydration & mild tightening)
Amount of treatments3–4 sessions, 2–3 weeks apart2–4 sessions3–4 sessions, 4 weeks apart2 sessions, 4 weeks apart
HighlightsFocuses on deep cellular repair and regenerationCombines hydration with collagen-boosting Amino AcidsProvides volume support, deepest regeneration, and structural supportExcellent for global hydration with minimal downtime

Ready to find out which booster is the best match for your unique skin? Book a consultation with a specialist today to discuss your goals and create a custom-tailored treatment plan!

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Book your 360° body appraisal

For a limited time, you can book a free body consultation. This twenty-minute appointment includes a detailed body assessment, similar to a body MOT, to help you understand what is achievable and how to plan ahead.

Trust our clinicians to create a bespoke body roadmap tailored to your unique 2026 goals.

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